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  • Title: Equithesin without chloral hydrate as an anaesthetic for rats.
    Author: Deacon RM, Rawlins JN.
    Journal: Psychopharmacology (Berl); 1996 Apr; 124(3):288-90. PubMed ID: 8740054.
    Abstract:
    In 1977 it was reported that chloral hydrate could cause adynamic ileus in rats, leading to morbidity and death. The symptoms were a swollen abdomen, lethargy and anorexia. However, chloral hydrate is still used as an anaesthetic, particularly in Equithesin mixture. We report that Equithesin without chloral hydrate is an effective anaesthetic, with a slightly reduced potency compared to Equithesin itself, and anaesthesia may be maintained for several hours by supplemental doses.
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