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  • Title: Immunohistochemical detection of virulence-associated antigens of Rhodococcus equi in pulmonary lesions of foals.
    Author: Madarame H, Takai S, Morisawa N, Fujii M, Hidaka D, Tsubaki S, Hasegawa Y.
    Journal: Vet Pathol; 1996 May; 33(3):341-3. PubMed ID: 8740709.
    Abstract:
    Rhodococcus equi was isolated from the lungs of six foals with bronchopneumonia. All isolates expressed 15-17-kd antigens by immunoblot analysis and contained a virulence-associated plasmid of 85 or 90 kb. Immunohistochemically, R. equi from all pulmonary lesions showed the expression of 15-17-kd antigens mainly in the phagocytic cells. The specific monoclonal antibody to 15-17-kd antigens of R. equi (MAb 10G5) may be an aid in the diagnosis of R. equi-induced pneumonia.
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