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  • Title: ITI (inter-alpha trypsin inhibitor) phenotyping by immunogold staining.
    Author: Kimura Y, Kido A, Nishizono T, Inoue T, Oya M.
    Journal: Gene Geogr; 1995 Dec; 9(3):191-6. PubMed ID: 8740897.
    Abstract:
    Polymorphism of Inter-alpha-Trypsin Inhibitor (ITI) was investigated in 685 unrelated Japanese individuals by isoelectric focusing followed by electroblotting and immunogold silver staining. The allele frequency estimates were ITI*1 = 0.455 +/- 0.013, ITI*2 = 0.516 +/- 0.013, ITI*3 = 0.028 +/- 0.0045 and ITI*4 = 0.001 +/- 0.001 and the phenotype frequencies fitted the Hardy-Weinberg equilibrium. The ITI system could be regarded as a potential genetic marker in paternity testing and anthropological studies.
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