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  • Title: Hyponatraemia and cerebral convulsion due to short term DDAVP therapy for control of enuresis nocturna.
    Author: Schwab M, Wenzel D, Ruder H.
    Journal: Eur J Pediatr; 1996 Jan; 155(1):46-8. PubMed ID: 8750810.
    Abstract:
    UNLABELLED: Desmopressin (DDAVP) is frequently used in the treatment of primary isolated enuresis nocturna if other approaches have failed. We report a further case of hyponatraemia and cerebral convulsion due to water intoxication after intranasal DDAVP application by a 6 year-old boy with enuresis. CONCLUSION: Although adverse reactions in DDAVP (e.g. hyponatraemia) are rare, it should not be considered as the first choice treatment of enuresis nocturna and only be used with caution.
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