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  • Title: Thrombolytic therapy in infants for femoral artery thrombosis following cardiac catheterisation.
    Author: Kothari SS, Kumar RK, Varma S, Saxena A.
    Journal: Indian Heart J; 1996; 48(3):246-8. PubMed ID: 8755008.
    Abstract:
    Little information is available on the use of thromobolytic therapy in infants for femoral artery thrombosis after cardiac catheterisation. We report 12 cases (mean age: 4 months; range: 1-9 months) who received intravenous streptokinase (3000 U/kg bolus, 1000 U/kg/h) infusion. Five of them had undergone transarterial balloon dilatation procedures. Streptokinase was administered 48 h after catheterisation and continued for 4-20 h (mean 11.5 h). No detailed haematologic monitoring was done during therapy. Distal pulses were restored in all the patients. No complications were seen except a minor local ooze in two patients. We found that intravenous streptokinase is a safe and effective therapy for femoral artery thrombosis following cardiac catheterisation in infants.
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