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  • Title: Use of allopurinol to treat visceral leishmaniosis in a dog.
    Author: Lester SJ, Kenyon JE.
    Journal: J Am Vet Med Assoc; 1996 Aug 01; 209(3):615-7. PubMed ID: 8755981.
    Abstract:
    Visceral leishmaniosis was diagnosed in a working sled dog on the basis of history, clinical signs, and identification of amastigotes in a skin biopsy specimen. Allopurinol was administered as sole treatment for the disease. The drug was given for 9 months, and, during this time, clinical signs of disease resolved. Laboratory abnormalities had resolved by 12 months after diagnosis and 3 months after treatment. The dog has been without medications for 19 months and remains free of clinical signs, has sired 2 litters, and functions well as lead sled dog for a team.
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