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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer.
    Author: Bouwmeester T, Kim S, Sasai Y, Lu B, De Robertis EM.
    Journal: Nature; 1996 Aug 15; 382(6592):595-601. PubMed ID: 8757128.
    Abstract:
    An abundant cDNA enriched in Spemann's organizer, cerberus, was isolated by differential screening. It encodes a secreted protein that is expressed in the anterior endomesoderm. Microinjection of cerberus mRNA into Xenopus embryos induces ectopic heads, and duplicated hearts and livers. The results suggest a role for a molecule expressed in the anterior endoderm in the induction of head structures in the vertebrate embryo.
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