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  • Title: Receptors for glucocorticoids in the human inner ear.
    Author: Rarey KE, Curtis LM.
    Journal: Otolaryngol Head Neck Surg; 1996 Jul; 115(1):38-41. PubMed ID: 8758627.
    Abstract:
    Glucocorticoid receptors were detected in the human inner ear. The highest concentration of glucocorticoid receptor protein was measured by enzyme-linked immunosorbent assay in the spiral ligament tissues; the lowest concentration of glucocorticoid receptors was measured in the macula of the saccule. The demonstration of the presence of glucocorticoid receptors in human Inner ear tissues provides a basis to consider the direct effects of glucocorticoid action on select inner ear cells, rather than assuming a systemic antiinflammatory or immunosuppressive effect during the therapeutic treatment of patients with given inner ear disorders.
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