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  • Title: Multiple endocrine neoplasia type 1 presenting as rosacea.
    Author: Creamer JD, Whittaker SJ, Griffiths WA.
    Journal: Clin Exp Dermatol; 1996 Mar; 21(2):170-1. PubMed ID: 8759212.
    Abstract:
    We present a case of malignant carcinoid initially diagnosed as rosacea. This patient was later found to have an additional functioning parathyroid tumour. Although a pituitary tumour was not identified, the association represents a probable case of multiple endocrine neoplasia type 1 (MEN 1). This autosomal dominant syndrome is characterized by tumours of the pancreas, parathyroid and pituitary. Inoperable carcinoid tumour is best treated with a long-acting somatostatin analogue, octreotide. A diagnosis of MEN 1 has important connotations for the proband's first-degree relatives, who should be entered into an appropriate screening programme.
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