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  • Title: [Adenoma of Brunner's gland: a rare cause of duodenal obstruction].
    Author: Rey P, Mambrini P, Barthet M, Orsoni P, Larroque O, Salducci J, Picaud R, Grimaud JC.
    Journal: J Chir (Paris); 1996 Jun; 133(4):162-6. PubMed ID: 8761069.
    Abstract:
    Pseudo-tumoral hyperplasia of the Brünner glands is an exceptional dysembryoplastic or hyperplastic lesion which develops in the submucosa of the supra papillary proximal duodenum. We report a case of Brünner adenoma which led to duodenal obstruction. In 50% of the cases, the adenoma was asymptomatic but non-specific signs may lead to barium studies. CT scan of the abdomen or esogastroduodenal endoscopy which rarely provides formal histological proof. Major complications (hemorrhage, duodenal obstruction) and lack of formal diagnosis often leads to surgery, ideally with tumor resection after duodenotomy. Other prodecures (simple observation, endoscopic polypectomy, duodenopancreatectomy, biliary or digestive bypass without tumorectomy) may be entertained depending on the functional status, the volume of the tumor, presence of complications and overall general status.
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