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  • Title: [Increase of alpha-fetoprotein in pancreatic endocrine tumors with hepatic metastases. Apropos of 2 cases].
    Author: Lesur G, Bergemer AM, Turner L, Parlier H, Bernades P, Dupuy P.
    Journal: Gastroenterol Clin Biol; 1996 Mar; 20(2):204-6. PubMed ID: 8761683.
    Abstract:
    We report two cases of metastatic non-functioning pancreatic endocrine tumour with very elevated plasma levels of alpha-fetoprotein. In these two cases, serial plasma levels of alpha-fetoprotein, initially normal, correlated well with hepatic tumour progression and were associated with fatal outcome. These results suggest that elevated plasma concentration of alpha-fetoprotein may be caused by metastatic pancreatic endocrine tumour and than alpha-fetoprotein serial measurement may be useful in prognostic evaluation.
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