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  • Title: [Angiomatoid malignant fibrous histiocytoma].
    Author: Fan Q, Allen PW.
    Journal: Zhonghua Bing Li Xue Za Zhi; 1996 Feb; 25(1):30-2. PubMed ID: 8762438.
    Abstract:
    By clinical, pathologic and immunohistochemical study on aniomatoid malignant fibrous histiocytoma, which is a relatively uncommon soft tissue tumor described by Enzinger in 1979, and often misdiagnosed, we are reporting 32 cases of this lesion. The distinctive histopathology were: (1) Cystic change filled with hemorrhagic fluid or blood, (2) surrounded by nests of fibroblastlike and histocyte-like cells and (3) intermingled with chronic inflammatory cells, (4) often surrounded by a fibrous pseudocapsule. Immunohistochemical staining done in 4 cases showed all to be positive in lysozyme, three positive in Mac 387 and CD 68. These results support their histiocytic origin. Follow-up information was available in 25 of 32 cases. All the 25 patients were alive, 4 with recurrence (16%), 1 with metastasis (4%). These results concur with the opinion that intrinsically, this is a low grade tumor.
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