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  • Title: [Pathology of the heart in AIDS. Study of 73 consecutive necropsies].
    Author: Politi Okoshi M, Rubens Montenegro M.
    Journal: Arq Bras Cardiol; 1996 Mar; 66(3):129-33. PubMed ID: 8762689.
    Abstract:
    PURPOSE: To study the incidence and the etiology of the cardiac lesions in AIDS patients. METHODS: The autopsy protocols and the filled slides of the heart from 73 consecutive AIDS patients were reviewed. There were, at least, 2 slides of each heart stained by haematoxylin-eosin; when indicated, Ziehl-Nielsen, Gram and Gomori Grocott stains were used. RESULTS: No cause of death was assigned to the heart. There was involvement of the heart in 66 (90%) cases. Marked atrophy of cardiac fibers with or without lipomatosis was observed in 38 patients. Interstitial infiltrates of myocardium were present in 38 necropsies and in 13 of these cases a probable pathogen was demonstrated: cryptococcus neoforms in three cases and mycobacteria tuberculosis, atypical mycobacteria, toxoplasma' gondii, trypanosoma cruzi and cytomegalovirus in two cases each. Bacterial endocarditis was found in 4 autopsies and Kaposi sarcome in one. The pericardium was involved in 22 cases; in 12 there was only non specific mononuclear infiltration. CONCLUSION: Autopsy examination of the heart from AIDS patients revealed frequent pathologic involvement.
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