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  • Title: Neutralizing antibodies to different proteins of African swine fever virus inhibit both virus attachment and internalization.
    Author: Gómez-Puertas P, Rodríguez F, Oviedo JM, Ramiro-Ibáñez F, Ruiz-Gonzalvo F, Alonso C, Escribano JM.
    Journal: J Virol; 1996 Aug; 70(8):5689-94. PubMed ID: 8764090.
    Abstract:
    African swine fever virus induces in convalescent pigs antibodies that neutralized the virus before and after binding to susceptible cells, inhibiting both virus attachment and internalization. A further analysis of the neutralization mechanisms mediated by the different viral proteins showed that antibodies to proteins p72 and p54 are involved in the inhibition of a first step of the replication cycle related to virus attachment, while antibodies to protein p30 are implicated in the inhibition of virus internalization.
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