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  • Title: [Study of the destruction of the sympathetic ganglia by the administration of guanethidine to newborn rats and mice].
    Author: Borisov MM, Mukhammedov A, Rodionov IM, Iarygin VN.
    Journal: Ontogenez; 1977; 8(3):311-3. PubMed ID: 876612.
    Abstract:
    Following the injection of guanethidine (25 mg/kg) to rats from the first day of life during 2 weeks, over 70% of sympathic neurons in the stellate ganglion die. If the injections are carried out during 4 weeks, over 99% of neurons die. The injection of guanethidine to mice during 5 weeks did not result in the destruction of nerve elements in the ganglion, as compared with the control.
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