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  • Title: Influence of once-daily administration of beta-adrenoceptor antagonists on arterial pressure and its variability.
    Author: Watson RD, Stallard TJ, Littler WA.
    Journal: Lancet; 1979 Jun 09; 1(8128):1210-3. PubMed ID: 87678.
    Abstract:
    Intra-arterial pressure was recorded over 24 h in hypertensive patients before and during long-term treatment with beta-adrenoceptor antagonists given once daily under standardised conditions. Arterial pressure was reduced throughout the 24 h after the last dose as was variability of pressure during physical activity; variability during sleep and rest did not change significantly.
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