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  • Title: Single-dose intramuscular ketorolac versus diclofenac for pain management in renal colic.
    Author: Stein A, Ben Dov D, Finkel B, Mecz Y, Kitzes R, Lurie A.
    Journal: Am J Emerg Med; 1996 Jul; 14(4):385-7. PubMed ID: 8768161.
    Abstract:
    A double-blind controlled study was designed to compare the effective- ness of a single intramuscular dose of 60 mg ketorolac with that of 75 mg diclofenac in the treatment of renal colic and to monitor side effects. Fifty-seven patients completed the study, 27 in the ketorolac group and 30 in the diclofenac group. Effectiveness of treatment was monitored by pain relief reported on a 4-point verbal scale at different time points. At 60 minutes 77.8% and 86.6% (P = 0.4) of patients, and at 120 minutes 81.5% and 96.6% (P = .1 5) of patients, reported significant pain relief following ketorolac and diclofenac doses, respectively. Both groups had an equal 92% significant pain relief at discharge from the emergency department. Both drugs were well tolerated by the patients. Ketorolac therefore, seems as effective as diclofenac in the treatment of renal colic.
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