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  • Title: Nonsterol related resistance in Ustilago maydis to the polyene antifungals, amphotericin B and nystatin.
    Author: Joseph-Horne T, Manning N, Holoman D, Kelly S.
    Journal: Phytochemistry; 1996 Jun; 42(3):637-9. PubMed ID: 8768319.
    Abstract:
    Two amphotericin B resistant mutants of Ustilago maydis were isolated following direct selection from a wild-type population. Each mutant was demonstrated to be cross-resistant to nystatin yet remained sensitive to azoles. Sterol analysis indicated a sterol profile similar to the parent strain, precluding the involvement of an alteration in ergosterol biosynthesis as the cause of polyene resistance.
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