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  • Title: Protein serine/threonine phosphatases.
    Author: Villafranca JE, Kissinger CR, Parge HE.
    Journal: Curr Opin Biotechnol; 1996 Aug; 7(4):397-402. PubMed ID: 8768897.
    Abstract:
    In the past year, the three-dimensional structures of two serine/threonine phosphatases, protein phosphatase-1 and protein phosphatase-2b (calcineurin), have been determined. The new information puts previous sequence comparisons and mutagenesis studies into a detailed structural perspective. The active-site structure and catalytic mechanism appear to be common to a variety of phosphoesterase enzymes.
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