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  • Title: Lipid peroxidation in hepatocellular carcinoma.
    Author: Iwagaki H, Hamazaki K, Matsubara N, Hiramatsu M, Orita K, Mori A.
    Journal: Acta Med Okayama; 1995 Dec; 49(6):313-5. PubMed ID: 8770241.
    Abstract:
    In this study, we measured free radicals and thiobarbituric acid-reactive substances (TBARS) in hepatocellular carcinoma and in non-cancerous liver parenchyma. There was a higher concentration of free radicals in malignant tissue than in non-cancerous tissue. In contrast, the level of TBARS was significantly (P < 0.01) lower than non-cancerous liver parenchyma. These paradoxical results suggested that antioxidative enzyme activity and/or inhibition of lipid peroxidation were higher in hepatocellular carcinoma.
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