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  • Title: Protonated polynucleotide structures, 20. Interaction between poly(dG)-poly(dC) and poly(rC).1.
    Author: Haas BL, Sarocchi MT, Guschilbauer W.
    Journal: Nucleic Acids Res; 1976 Jun; 3(6):1549-59. PubMed ID: 8771.
    Abstract:
    A study of the interaction between poly(dG)-poly(dC) and poly(rC) demonstrates that, at neutral pH and high ionic strength, there is replacement of the dC strand by poly(rC). At acid pH, formation of a triple-stranded complex which equally may involve the replacement phenomenon is observed. There is no evidence for interaction at neutral pH between poly(dG)-poly(dC) and oligo(rC), while a three-stranded complex is formed at acid pH. These data are consistent with the studies of comparative stabilities of double stranded deoxy or ribo polymers and deoxy-ribo hybrids.
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