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  • Title: Effect of gabapentin (Neurontin) [corrected] on mood and well-being in patients with epilepsy.
    Author: Dimond KR, Pande AC, Lamoreaux L, Pierce MW.
    Journal: Prog Neuropsychopharmacol Biol Psychiatry; 1996 Apr; 20(3):407-17. PubMed ID: 8771597.
    Abstract:
    1. Global improvement data from five double-blind clinical trials of gabapentin as add-on therapy in patients with epilepsy were reviewed to assess the effects of gabapentin on mood. 2. One hundred and ninety-four (46%) of 423 gabapentin-treated patients reported improvements in general well-being as compared with 79 (29%) of the 271 placebo-treated patients. 3. Findings support anecdotal reports of improved affective status among patients taking gabapentin and suggest that the study of gabapentin in psychiatric populations may be warranted.
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