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  • Title: [The interferon therapy of patients with chronic viral hepatitis: the factors affecting the treatment results].
    Author: Kokoreva LN, Zmyzgova AV, Shalygina NB.
    Journal: Ter Arkh; 1996; 68(2):10-4. PubMed ID: 8771646.
    Abstract:
    The paper presents clinicoimmunological characterization or therapeutic efficacy of alpha-interferons produced in Russia and criteria of their administration in patients with chronic viral hepatitis. A 6 to 12 months course (single dose 1 x 10(6)-3 x 10(6) IU improves the disease running, hepatic function and corrects immune status in 55.6% of patients with chronic active hepatitis eventuating in liver cirrhosis and in 57.9% of patients in chronic active hepatitis of moderate activity. Alpha-interferons are indicated in chronic active hepatitis and cirrhosis under high activity of cytolytic process, immunodeficiency, weak autoimmune process and protein shifts.
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