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  • Title: Benzodiazepine withdrawal syndrome seizures.
    Author: Martínez-Cano H, Vela-Bueno A, de Iceta M, Pomalima R, Martínez-Gras I.
    Journal: Pharmacopsychiatry; 1995 Nov; 28(6):257-62. PubMed ID: 8773293.
    Abstract:
    In this study, we present five cases of seizures following withdrawal of flunitrazepam, lorazepam, or triazolam, representing 3% of a sample consisting of 153 patients dependent on benzodiazepines. Both abrupt cessation of benzodiazepine intake and high-dose use seem to be critical for the appearance of seizures. Pharmacological features, such as short elimination half-life and high potency, might explain the higher risk of seizures observed in these patients.
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