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  • Title: Invasive vulvar carcinoma in two women infected with human immunodeficiency virus.
    Author: Wright TC, Koulos JP, Liu P, Sun XW.
    Journal: Gynecol Oncol; 1996 Mar; 60(3):500-3. PubMed ID: 8774667.
    Abstract:
    This report presents two HIV-infected women who developed invasive squamous cell carcinoma of the vulva. One patient was diagnosed with Stage II vulvar cancer 4 years after surgical excision of VIN. This patient underwent a hemivulvectomy and external-beam radiation therapy, but has subsequently developed recurrent vulvar cancer. The other patient was diagnosed with stage IV invasive vulvar cancer 1 year after the diagnosis of VIN and died of invasive vulvar cancer 11 months later. VIN should be considered a serious condition in HIV-infected women and clinicians should be careful to examine the vulva and perianal region in all HIV-infected women.
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