These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Dopamine receptor binding enhancement accompanies lesion-induced behavioral supersensitivity.
    Author: Creese I, Burt DR, Snyder SH.
    Journal: Science; 1977 Aug 05; 197(4303):596-8. PubMed ID: 877576.
    Abstract:
    The binding of [3H]haloperidol to rat striatal dopamine receptors increases after lesion (made by injection of 6-hydroxydopamine) of the nigrostriatal dopamine pathway in those rats which are behaviorally supersensitive, as reflected by apomorphine-induced contralateral rotations. The enhanced binding is associated with an increased number of receptor sites with no change in their affinity.
    [Abstract] [Full Text] [Related] [New Search]