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  • Title: [Spontaneously involuting metastatic seminoma of the testis ("burned-out seminoma"). Report of a case presenting with supraclavicular adenopathy].
    Author: Weber O, Hubert J, Grignon Y, Mangin P.
    Journal: Prog Urol; 1996 Apr; 6(2):278-81. PubMed ID: 8777424.
    Abstract:
    Metastatic testicular germ cell tumours with complete involution of the primary site, or "burned-out tumour", constitute a classical but rare entity, whether the initial cell type is seminomatous or non-seminomatous. The authors report one case of this type of tumour. The diagnosis is primarily based on ultrasonography, indicating the need for orchidectomy in the presence of an anomaly, followed by histology, revealing a fibrous scar with no tumour cells. Aetiopathogenic hypotheses are divided between ischaemic and immunological theories. Scrotal ultrasonography and tumour marker assays should be performed systematically in the presence of retroperitoneal adenopathy with normal testicular clinical examination.
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