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  • Title: Rollinecins A and B: two new bioactive annonaceous acetogenins from Rollinia mucosa.
    Author: Shi G, Ye Q, He K, McLaughlin JL, MacDougal JM.
    Journal: J Nat Prod; 1996 May; 59(5):548-51. PubMed ID: 8778247.
    Abstract:
    Two new mono-THF ring acetogenins, rollinecins A (1) and B (2), were isolated from the partitioned ethanolic extracts of the leaves of Rollinia mucosa (Annonaceae) by activity-directed fractionation. 1 and 2 are epimeric at the C-14 carbinol stereocenter. Their absolute stereochemical structures were solved by preparing their respective per-Mosher ester derivatives. 1 and 2 showed equivalent and selective in vitro activities against several human solid tumor cell lines.
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