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  • Title: Biocompatibility of polysulfone I. Surface modifications and characterizations.
    Author: Khang G, Lee HB, Park JB.
    Journal: Biomed Mater Eng; 1995; 5(4):245-58. PubMed ID: 8785509.
    Abstract:
    Surface treatments by nonionic surfactant (Brij) coating and air-plasma glow discharge treatment onto polysulfone have been investigated to improve its surface properties. Surface treated samples were characterized by measurement of contact angle by a goniometer, Fourier transform infrared spectroscopy in the attenuated total reflectance mode (FTIR-ATR), and electron spectroscopy for chemical analysis (ESCA). The contact angles of the nonionic surfactant coated films decreased from 66.6 +/- 2.1 degrees to nearly 0 degrees due to hydrophilic polyethylene oxide (PEO) chain segment of the nonionic surfactant, and those of air-plasma treated films also decreased from 66.6 degrees to about 22 degrees with a treatment time of less than 5 s. ESCA analysis of air-plasma treated films indicates the incorporation of oxygen molecules onto polysulfone surface lowers the water contact angle. These modified techniques can be used to prevent platelet adhesion onto polysulfone surfaces.
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