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  • Title: [Pulse oximetry and methemoglobinemia].
    Author: Moretti S, Jouvet P, Schleiermacher G, Hubert P, Doz F, Zucker JM, Cloup M.
    Journal: Arch Pediatr; 1996 Mar; 3(3):258-60. PubMed ID: 8785565.
    Abstract:
    BACKGROUND: Cyanosis associated to low oxygen saturation may reveal hemoglobin pathology. CASE REPORT: A 3 year-old child had a nephroblastoma with pleural effusion. He suddenly developed persistent cyanosis despite pleural effusion drainage; transcutaneous and measured oxygen saturations were low and PaO2 on arterial blood gases was high. Methemoglobinemia was diagnosed, due to prilocaine-lignocaine cream used for local anesthesia, associated to partial G6PD deficiency. The methemoglobinemia disappeared after methylene blue treatment. CONCLUSION: Cyanosis with low oxygen saturation and high or normal PaO2 should lead to the search of a hemoglobin pathology, especially methemoglobinemia, by appropriate methods.
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