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  • Title: [POEMS syndrome: role and value of interleukin-6].
    Author: Andrès E, Courouau F, Kaltenbach G, Maloisel F, Imler M.
    Journal: Rev Med Interne; 1996; 17(2):145-9. PubMed ID: 8787086.
    Abstract:
    POEMS syndrome is a systemic disorder with peripheral neuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes. The association of POEMS syndrome with lympho-proliferative disorder is very commun. The pathogenesis remains poorly understood but implication of cytokines (interleukins 1 and 6) is suspected. We report a case of a classic POEMS syndrome (with polyneuropathy, hepatomegaly, diabetes melitus, hyperpigmentation, monoclonal IgG lambda, anasarca and solitary plasmocytoma), associated with high serum levels of interleukin 6.
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