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  • Title: Adrenomedullin-immunoreactive neurons in the paraventricular and supraoptic nuclei of the rat.
    Author: Ueta Y, Kitamura K, Isse T, Shibuya I, Kabashima N, Yamamoto S, Kangawa K, Matsuo H, Eto T, Yamashita H.
    Journal: Neurosci Lett; 1995 Dec 29; 202(1-2):37-40. PubMed ID: 8787825.
    Abstract:
    The existence of adrenomedullin (AM) in the rat hypothalamus was examined by immunohistochemistry. AM-immunoreactive neurons were found in the supraoptic nucleus (SON) and in the magnocellular parts of the paraventricular nucleus (PVN). The co-existence of AM-, oxytocin- and/or vasopressin-immunoreactivity was identified in the same neurons in the hypothalamus. The results suggest that the AM may play a role in neurotransmission or in cardiovascular control with neurohypophyseal hormones.
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