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Title: TDT with covariates and genomic screens with mod scores: their behavior on simulated data. Author: Rice JP, Neuman RJ, Hoshaw SL, Daw EW, Gu C. Journal: Genet Epidemiol; 1995; 12(6):659-64. PubMed ID: 8787990. Abstract: We describe an extension to the TDT (transmission/disequilibrium test) which allows for more than two marker alleles and for covariates measured on the parent or offspring. We also describe a systematic genomic search where the mod score (maximized lod score) is computed for each marker under constraints on the population prevalence or penetrances of a single locus.[Abstract] [Full Text] [Related] [New Search]