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Pubmed for Handhelds

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  • Title: Inexpensive continuous-infusion swivel: towards more physiological measurements.
    Author: Frübeck G.
    Journal: Physiol Res; 1995; 44(2):121-126. PubMed ID: 8789324.
    Abstract:
    A cheap, simple and fast procedure of building an infusion swivel is described for both short- and long-term experiments in rats. To assemble the swivel, plastic laboratory syringe elements, needles and a three-way stopcock are used. The swivel avoids cannula-kinking and permits animals free movement inside the cage. In addition, the gadget presented is inexpensive enough to make it disposable. Further advantages of the self-made infusion swivel depend on its disposability, it is time-saving, simplifies blood sampling or administration of drugs and prevents contamination, when using radiolabelled products. The haemodynamics and metabolism of rats subjected to restraint stress or ether-anaesthetized rats significantly differ from those of conscious freely moving animals. Whereas restraint stress provoked a more pronounced increase of blood pressure and heart rate, ether anaesthesia induced a 19% rise in serum glucose. Thus, the device described in this study provides more physiological experimental conditions.
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