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  • Title: Utility of technetium-99m-sestamibi to assess osseous tumor spread.
    Author: Glaser C, Pruckmayer M, Staudenherz A, Rasse M, Lang S, Leitha T.
    Journal: J Nucl Med; 1996 Sep; 37(9):1526-8. PubMed ID: 8790209.
    Abstract:
    We report the staging results and the surgical outcome of a male patient with squamous-cell carcinoma in the floor of the mouth and a bone SPECT scan suggestive of local tumor infiltration of the mandible. Additional 99mTc-sestamibi SPECT imaging of the primary tumor and superimposing of both studies excluded osseous tumor spread and less extensive surgery was performed. Pathohistological examination confirmed the scintigraphic results and indicated a nonspecific periostal reaction as the cause of the positive bone scan. Nevertheless, a high-resolution camera and careful superimposition of both studies is mandatory if the differential diagnosis of an osseous tumor spread of a malignant tumor in the floor of the mouth and possibly less extensive surgery is at stake.
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