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  • Title: Hepatocellular carcinoma with pleural metastasis complicated by hemothorax.
    Author: Takagi H, Shimoda R, Uehara M, Takayama H, Yamada T, Ojima T, Abe T, Mori M, Takehara K, Suka K, Nagamine T, Yamasaki S, Barber A.
    Journal: Am J Gastroenterol; 1996 Sep; 91(9):1865-6. PubMed ID: 8792722.
    Abstract:
    Hemothorax can be caused by rupture of hepatocellular carcinoma (HCC). Hemoperitoneum is a well-known cause of death caused by rupture of a primary HCC lesion. Rupture of a HCC metastasis has not been adequately described. This is the first report of a HCC patient who died of hemothorax due to rupture of a pleural metastasis. The patient, a woman, died in respiratory failure 2 wk after rupture of her HCC metastasis in the pleura. Autopsy revealed moderately differentiated HCC in the liver, lung, and pleura. We discuss treatment options for ruptured pleura-based HCC metastases.
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