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  • Title: Aspergillus laryngotracheobronchitis presenting as stridor in a patient with peripheral T cell lymphoma.
    Author: Kuo PH, Lee LN, Yang PC, Chen YC, Luh KT.
    Journal: Thorax; 1996 Aug; 51(8):869-70. PubMed ID: 8795683.
    Abstract:
    Invasive aspergillosis is a serious opportunistic infection in immunocompromised patients. The case history is described of a 44 year old patient with peripheral T cell lymphoma who developed hoarseness and stridor after chemotherapy. Aspergillus fumigatus was isolated repeatedly from the sputum. Bronchoscopic examination showed symmetrical creamy-white exophytic lesions involving both vocal cords and the supraglottic area. There was diffuse tracheobronchitis with multiple raised cream-coloured plaques in the trachea which histologically consisted of numerous septate branching hyphae consistent with Aspergillus species. The lesions responded to systemic treatment with amphotericin B.
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