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  • Title: Mastocytosis-induced nyctalopia.
    Author: Lesser RL, Brodie SE, Sugin SL.
    Journal: J Neuroophthalmol; 1996 Jun; 16(2):115-9. PubMed ID: 8797168.
    Abstract:
    Systemic mastocytosis is characterized by an increased number of mast cells in multiple organs particularly skin. A 55-year-old man with mastocytosis presented with nyctalopia caused by malabsorption of vitamin A. Diagnosis was made by documenting a low vitamin A level and an ERG that showed rod-cone deficiency with rods affected more than cones. Vitamin A therapy led to return of good visual function. To our knowledge, this is the first reported case of mastocytosis induced nyctalopia. Vitamin A deficiency should be considered as a potential cause of visual loss in patients with sudden onset of night blindness.
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