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  • Title: Avasucular necrosis of pheochromocytoma followed by spontaneous remission.
    Author: Atuk NO, Teja K, Mondzelewski P, Turner SM, Selden RF.
    Journal: Arch Intern Med; 1977 Aug; 137(8):1073-5. PubMed ID: 879946.
    Abstract:
    Following an acute spontaneous hypertensive crisis and shock a patient with pheochromocytoma was found to have an exceedingly high catecholamine excretion rate. After this episode, the patient remained normotensive and urinary excretion of catecholamines returned to normal. During surgery, a large pheochromocytoma was found and removed that showed avascualr necrosis. In phenochromocytoma, a sudden and exceedingly high rate of catecholamine release may cause intense vasoconstriction both generally and within the tumor itself. In this patient, avascular tumor necrosis led to a spontaneous remission of clinical symptoms.
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