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  • Title: Amphotericin B lipid complex treatment of a leukemic child with disseminated Fusarium solani infection.
    Author: Patterson TS, Barton LL, Shehab ZM, Hutter JJ.
    Journal: Clin Pediatr (Phila); 1996 May; 35(5):257-60. PubMed ID: 8804544.
    Abstract:
    We report a case of Fusarium solani infection in a 2 1/2-year-old girl with acute lymphoblastic leukemia and severe neutropenia. The infection, initially limited to her sinuses, became disseminated, as evidenced by the development of a characteristic cutaneous lesion on her left leg after a cumulative dose of amphotericin B of 18.3 mg/kg. Amphotericin B lipid complex (ABLC), 5 mg/kg/day, in conjunction with repeated surgical debridement of the sinuses and correction of neutropenia with granulocyte colony stimulating factor (GCSF), led to clinical and mycologic cure.
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