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  • Title: Cyproterone acetate: II. failure to reduce sperm fertility in the surgically separated epididymis of rat.
    Author: Chatterjee A, Pal AK, Ray P, Basu R.
    Journal: Contraception; 1977 Apr; 15(4):429-34. PubMed ID: 880818.
    Abstract:
    The effects of cyproterone acetate, administered via sc capsules, on the surgically separated rat epididymis and on fertility were studied. Treatment with the antiandrogen reduced the weight of the surgically separated epididymis. However, short- or long-term administration of small quantities of cyproterone acetate had no effect on the fertility of epididymal spermatozoa. The results appear to show that epididymal spermatozoa are capable of fertilization even at low levels of androgens resulting from treatment with cyproterone acetate.
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