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  • Title: [Low doses of heparin in the prevention of postoperative thrombosis of deep veins of the lower limbs].
    Author: Baeshko AA, Shorokh GP.
    Journal: Klin Med (Mosk); 1995; 73(5):60-2. PubMed ID: 8815283.
    Abstract:
    As shown by 125I-fibrinogen, in the course of 10-year investigation on low-dose heparin given in low doses (15000 U/day) to prevent postoperative thrombosis in the deep veins of the lower limbs, the investigators succeeded in the reduction of the thrombosis occurrence from 32 to 8%. Out of 3700 surgical patients (age over 40, duration of surgery 1 hour and more) pretreated with anticoagulant only 6 (0.16%) died of pulmonary artery thrombosis. This means that relevant lethality decreased 9-fold compared to controls untreated with prophylactic heparin. Serious hemorrhagic complication due to low-dose heparin were not observed.
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