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  • Title: A community prevalence study of antibodies to hepatitis A and E in inner-city London.
    Author: Bernal W, Smith HM, Williams R.
    Journal: J Med Virol; 1996 Jul; 49(3):230-4. PubMed ID: 8818970.
    Abstract:
    The seroprevalence of antibodies to hepatitis E virus (HEV) and hepatitis A virus (HAV) was determined in a community-based sample in innercity London where socioeconomic conditions were expected to result in a high prevalence of antibodies to HAV, and in which the presence of immigrants from the developing world pose a risk of imported infection of both HAV and HEV. The seroprevalence of anti-HAV was 45.1% in UK born subjects and 69.7% in non-UK born subjects and each group showed differing patterns of age-specific seroprevalence. The seroprevalence rates of anti-HEV was 3.9% in UK born subjects and 8.8% in non-UK born subjects. The age-specific seroprevalence of the UK born group is suggestive of a cohort effect. The data suggest a low circulation of HEV in inner-city London, remaining uncommon relative to HAV.
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