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  • Title: Chronic lung disease secondary to ammonia inhalation injury: a report on three cases.
    Author: de la Hoz RE, Schlueter DP, Rom WN.
    Journal: Am J Ind Med; 1996 Feb; 29(2):209-14. PubMed ID: 8821365.
    Abstract:
    Inhalation of highly hydrosoluble toxicants, like ammonia, can be associated with chronic lung diseases, which have been partially characterized. We present the case of three patients who were evaluated 2 years after massive exposure to ammonia in occupational settings. They presented with chronic dyspnea, and clinical pictures consistent with restrictive lung dysfunction, obstructive lung disease, and bronchial hyper-reactivity and small airways disease, respectively. The findings in 94 reported cases of inhalation injury due to massive exposure to ammonia are reviewed; in 35 cases follow-up for at least 1 year was available. The range of chronic pulmonary diseases associated with ammonia inhalation injury is reviewed, and suggestions for appropriate diagnostic evaluation are made.
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