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  • Title: YM-24074, a new peptide antibiotic. II. Structural elucidation.
    Author: Sato T, Takebayashi Y, Tokunaga T, Ozasa T.
    Journal: J Antibiot (Tokyo); 1996 Aug; 49(8):811-4. PubMed ID: 8823515.
    Abstract:
    YM-24074 (formerly called YL-01869P) is a new antibiotic and type I collagenase inhibitor. The structure of this compound was elucidated by spectroscopic analysis and confirmed by acid degradation to be N-(1"-acetyl-3"-methylbutyl)-2- [2'-[(N-hydroxycarbamoyl)methyl]heptanoyl]-hexahydropyrid azine-3-carboxamide. The stereochemistry of two of three chiral centers was determined by degradation products to be 3S, 2'R.
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