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  • Title: Absence of restricted T cell receptor V beta repertoire in skin lesions of a patient with both psoriasis vulgaris and lichen planus.
    Author: Yamamoto T, Katayama I, Nishioka K.
    Journal: Dermatology; 1996; 192(1):67-9. PubMed ID: 8832958.
    Abstract:
    In a patient with both lichen planus and psoriasis, and suffering from hepatitis C virus infection, we examined the T cell receptor (TCR) Vb repertoire by reverse transcriptase polymerase chain reaction in skin lesions from psoriasis and lichen planus. A variety of rearranged variable TCR genes was found in the skin lesions, and the TCR Vb repertoire of the infiltrating T cells was not restricted. Although different patterns of expression were observed in the two lesions, TCR Vb 2 and 7 were commonly found.
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