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  • Title: Study of lithogenicity of bile among patients suffering from cholecystolithiasis and among patients not suffering from this disease.
    Author: Kamocki Z, Dadan H, Zimnoch L, Markiewicz W, Zalewski B, Okulczyk B.
    Journal: Rocz Akad Med Bialymst; 1995; 40(2):267-75. PubMed ID: 8834609.
    Abstract:
    On the basis of biochemical and morphological research, the authors decided to attempt to determine the degree of lithogenicity of the bile among patients suffering from cholecystolithiasis (100 patients) and those not suffering from this disease (31 patients). Having analyzed the obtained data, it can be concluded that the degree of lithogenicity of bile is influenced by the concentration of cholesterol, bile acids and phospholipids as well as the damage of the liver and of the wall of the gallbladder as well as its kinetics. Lithogenic bile was noticed in 84% of the patients of group I and in 54% in group II. However, the degree of lithogenicity was significantly higher in patients suffering from cholecystolithiasis. According to the authors, the degree of lithogenicity is the deciding factor in the creation of bile stones.
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