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  • Title: Lumbar chymopapain nucleolysis.
    Author: Javid MJ, Nordby EJ.
    Journal: Neurosurg Clin N Am; 1996 Jan; 7(1):17-27. PubMed ID: 8835141.
    Abstract:
    Chemonucleolysis with chymopapain is indicated in the majority of patients who are candidates for surgery for intractable sciatica due to herniated nucleus pulposus. It is safer, as effective, and cheaper than standard surgical discectomy, providing that patients are well selected and the procedure is properly performed. Because the indication for chemonucleolysis is not limited to contained discs, it has proved to be more effective than percutaneous discectomy. At present, of all percutaneous methods, lumbar chymopapain nucleolysis is the only procedure that has withstood the test of time. It is an attractive alternative to surgical discectomy and should be presented for consideration to patients who meet the criteria for the procedure.
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