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  • Title: Carboxyl terminal region of the MukB protein in Escherichia coli is essential for DNA binding activity.
    Author: Saleh AZ, Yamanaka K, Niki H, Ogura T, Yamazoe M, Hiraga S.
    Journal: FEMS Microbiol Lett; 1996 Oct 01; 143(2-3):211-6. PubMed ID: 8837474.
    Abstract:
    The purified MukB protein of Escherichia coli has DNA binding activity and nucleotide binding activity. We have isolated a mutation, mukB1013, causing a substitution of valine at position 1379 to leucine. This mutant MukB protein was defective for DNA binding, while the ATP binding activity remained unaffected. A truncated MukB protein that is short of 109 amino acids from the C-terminus failed to bind DNA.
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