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Title: Correlated inhibition of ribosomal RNA synthesis and silver staining by actinomycin D. Author: Hofgärtner FJ, Krone W, Jain K. Journal: Hum Genet; 1979 Apr 05; 47(3):329-33. PubMed ID: 88405. Abstract: Preferential inhibition of the synthesis of ribosomal RNA by low doses of actinomycin D was used to investigate the quantitative relationship between the intensity of silver staining of nucleoli and the rate of RNA-synthesis. The two parameters were found to be strongly correlated in human diploid fibroblasts.[Abstract] [Full Text] [Related] [New Search]